Detalhe da pesquisa
1.
Mapping enzyme activity in living systems by real-time mid-infrared photothermal imaging of nitrile chameleons.
Nat Methods
; 21(2): 342-352, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191931
2.
Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent ß-amyloid generation.
Cell
; 147(3): 615-28, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22036569
3.
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease.
Nature
; 586(7831): 735-740, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879487
4.
Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo.
Nat Chem Biol
; 19(12): 1448-1457, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37322156
5.
HuM195 and its single-chain variable fragment increase Aß phagocytosis in microglia via elimination of CD33 inhibitory signaling.
Mol Psychiatry
; 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383769
6.
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.
Nat Immunol
; 13(7): 642-50, 2012 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22610140
7.
Cu(II)-Catalyzed Enantioselective Aza-Friedel-Crafts Reaction of 1-Naphthols and Electron-Rich Phenols with Isatin-Derived Ketimines.
Chemistry
; : e202304118, 2024 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38433408
8.
Blending Aryl Ketone in Covalent Organic Frameworks to Promote Photoinduced Electron Transfer.
J Am Chem Soc
; 145(16): 9198-9206, 2023 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37125453
9.
γ-Secretase fanning the fire of innate immunity.
Biochem Soc Trans
; 51(4): 1597-1610, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37449907
10.
Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aß production under hypoxia and cerebral hypoperfusion.
Mol Psychiatry
; 27(10): 4264-4273, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764706
11.
New Binaphthyl-Proline-Based Chiral Ligands Bearing Imidazoline Groups: Design, Synthesis, and Their Application in Enantioselective Conjugate Addition of 4-Hydroxycoumarin and Related Nucleophiles to ß,γ-Unsaturated α-Ketoesters.
J Org Chem
; 88(21): 14928-14944, 2023 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874252
12.
Enantioselective Friedel-Crafts Alkylation of Indoles with ß,γ-Unsaturated α-Ketoesters Catalyzed by New Copper(I) Catalysts.
J Org Chem
; 88(5): 3046-3053, 2023 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791262
13.
Copper(II)-Catalyzed Enantioselective Aza-Friedel-Crafts Reaction of Indoles with Isatin-Derived N-Boc-Ketimines.
J Org Chem
; 88(20): 14345-14350, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37791977
14.
Binaphthyl-Proline Hybrid Chiral Ligands: Modular Design, Synthesis, and Enantioswitching in Cu(II)-Catalyzed Enantioselective Henry Reactions.
J Org Chem
; 88(12): 7651-7659, 2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36106472
15.
Enantioselective Michael addition of malonates to ß,γ-unsaturated α-ketoesters catalysed by Cu(II) complexes bearing binaphthyl-proline hybrid ligands.
Org Biomol Chem
; 21(8): 1764-1770, 2023 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36723244
16.
Carbon and nitrogen sources consumption by ale and lager yeast strains: a comparative study during fermentation.
Appl Microbiol Biotechnol
; 107(22): 6937-6947, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37704770
17.
Diffusion-Weighted Imaging as a Quantitative Imaging Biomarker for Predicting Proliferation Rate in Hepatocellular Carcinoma: Developing a Radiomics Nomogram.
J Comput Assist Tomogr
; 47(4): 539-547, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36877762
18.
LI-RADS category 3, 4, and M observations: a multiple parameters diagnostic model for hepatocellular carcinoma.
Acta Radiol
; 64(12): 2977-2986, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37753552
19.
γ-Secretase inhibitors and modulators: Mechanistic insights into the function and regulation of γ-Secretase.
Semin Cell Dev Biol
; 105: 43-53, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32249070
20.
miRTarBase 2020: updates to the experimentally validated microRNA-target interaction database.
Nucleic Acids Res
; 48(D1): D148-D154, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647101